ALK (Phospho-Tyr1586) rabbit pAb

簡(jiǎn)要描述：SourceRabbitApplicationsIHC

產(chǎn)品型號(hào)：
廠商性質(zhì)：生產(chǎn)廠家
更新時(shí)間：2025-10-15
訪問量：179

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產(chǎn)品分類

CLASSIFICATION

Primary Antibodies

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詳細(xì)介紹

Source

Rabbit
Applications

IHC,WB
Reactivity

Human:Y1586, Mouse:Y1592
Dilution

IHC 1:50-200, WB 1:500-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous phospho levels of ALK (Phospho-Tyr1586) at Human:Y1586, Mouse:Y1592
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human ALK (Phospho-Tyr1586)
Uniprot No

Q9UM73
Alternative names

ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

anaplastic lymphoma receptor tyrosine kinase(ALK) Homo sapiens This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome
Other

ALK, ALK (Phospho-Tyr1586)
Concentration

1 mg/ml

Product	Reactivity	Applications	Conjugation	Catalog	Images

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ALK (Phospho-Tyr1586) rabbit pAb

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Concentration

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